A system and method for endpoint selection in a global accelerator system. The global accelerator system includes client devices communicating with a global access point to access various endpoints that can host services. Multiple endpoints are grouped geographically according to different data centers. Client service requests are received at a global access point, which in turns selects an endpoint to service the request. A selection mechanism utilized by the global access point implements a distribution algorithm that facilitates that distribution of endpoint requests according to a product of distribution criteria and geographic criteria. Additionally, the global access point can then identify individual endpoints within the group to process the request using a consistent hashing algorithm that ensures an endpoint can be continuously selected over the course of interaction with a client.