Invention Grant
- Patent Title: Genotyping polyploid loci
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Application No.: US16305818Application Date: 2017-06-02
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Publication No.: US11456055B2Publication Date: 2022-09-27
- Inventor: Ryan Kelley
- Applicant: Illumina, Inc.
- Applicant Address: US CA San Diego
- Assignee: Illumina, Inc.
- Current Assignee: Illumina, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Weaver Austin Villeneuve & Sampson LLP
- International Application: PCT/US2017/035751 WO 20170602
- International Announcement: WO2017/210603 WO 20171207
- Main IPC: G16B20/20
- IPC: G16B20/20 ; G16B40/30 ; G16B5/20 ; G16B40/20

Abstract:
Provided are methods, systems, and computer products for genotyping polyploid organisms, as well as diploid organisms. The provided methods use an allele-intensity model to generate cluster definitions. The allele-intensity model relates allele counts of different genotypes to signal intensities generated by the genotyping platform. The model also includes a capability to update cluster positions obtained from a maximum likelihood model using a Bayesian method.
Public/Granted literature
- US20200321075A1 GENOTYPING POLYPLOID LOCI Public/Granted day:2020-10-08
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