Invention Grant
- Patent Title: Quinolin-2(1H)-one inhibitors of Late SV40 Factor
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Application No.: US17464260Application Date: 2021-09-01
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Publication No.: US11458132B2Publication Date: 2022-10-04
- Inventor: Scott Edward Schaus , Ulla Hansen , Emily Ann York , Niranjana Pokharel
- Applicant: TRUSTEES OF BOSTON UNIVERSITY
- Applicant Address: US MA Boston
- Assignee: TRUSTEES OF BOSTON UNIVERSITY
- Current Assignee: TRUSTEES OF BOSTON UNIVERSITY
- Current Assignee Address: US MA Boston
- Agency: Nixon Peabody LLP
- Agent Ronald I. Eisenstein; Ravinderjit Braich
- Main IPC: A61K31/4741
- IPC: A61K31/4741 ; A61P35/00 ; C07D491/056 ; C07D215/227
Abstract:
The present invention is directed to compositions, methods and kits for treatment of cancer, e.g., hepatocellular carcinoma (HCC). In some embodiments, the present invention discloses the use of a small-molecule compounds of Formula (I) to inhibit tubulin acetylation, to inhibit cell migration, or to modulate cell compaction.
Public/Granted literature
- US20220062272A1 QUINOLIN-2(1H)-ONE INHIBITORS OF LATE SV40 FACTOR Public/Granted day:2022-03-03
Information query
IPC分类:
