A process for operating an extrusion system is provided. An extrusion device is provided that has at least two extrusion pistons operable with different feed ratios. The process involves storing a ratio of feed rates of the extrusion pistons in a storage device of the control device in dependence on the second signal. A least one drive device is actuated by the control device for displacing the two extrusion pistons into a start position, in which a plunger of the first extrusion piston substantially abuts the first cartridge of the cartridge device and a plunger of the second extrusion piston substantially abuts the second cartridge the cartridge device. The at least one drive device is actuated by the control device with a ratio of feed rates stored in the storage device of the control device for the extrusion pistons at user request.