Invention Grant
- Patent Title: Crystalline form of 1-(5-(2,4-difluorophenyl)-1-((3-fluorophenyl)sulfonyl)-4-methoxy-1H-pyrrol-3-yl)-N-methylmethanamine salt
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Application No.: US17151901Application Date: 2021-01-19
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Publication No.: US11459297B2Publication Date: 2022-10-04
- Inventor: Aeri Kim , Kwan Hyung Cho
- Applicant: Daewoong Pharmaceutical Co., Ltd.
- Applicant Address: KR Gyeonggi-do
- Assignee: Daewoong Pharmaceutical Co., Ltd.
- Current Assignee: Daewoong Pharmaceutical Co., Ltd.
- Current Assignee Address: KR Gyeonggi-do
- Agency: White & Case LLP
- Priority: KR10-2016-0036080 20160325
- Main IPC: C07D207/48
- IPC: C07D207/48 ; A61K31/40

Abstract:
The present invention provides a novel crystalline form I of hydrochloride, a crystalline form II of hydrochloride, a crystalline form of succinate, a crystalline form of tartrate, a crystalline form I of fumarate and a crystalline form II of fumarate of 1-(5-(2,4-difluorophenyl)-1-((3-fluorophenyl)sulfonyl)-4-methoxy-1H-pyrrol-3-yl)-N-methylmethanamine. The above-described novel crystalline forms have high solubility in water and excellent stability under moisture-proof conditions and high-humidity exposure conditions, and thus can be pharmaceutically used.
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