![Substituted 2-azabicyclo[3.1.0]hexanes as TRK kinases inhibitors](/docs/US/2022-10-04/US11459332B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted 2-azabicyclo[3.1.0]hexanes as TRK kinases inhibitors
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Application No.: US16980487Application Date: 2019-03-13
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Publication No.: US11459332B2Publication Date: 2022-10-04
- Inventor: Hongbin Liu , Haohan Tan , Chengxi He , Xianlong Wang , Qihong Liu , Zhifu Li , Zuwen Zhou , Yuwei Gao , Lihua Jiang , Li Linghu , Shu Lin , Xingdong Zhao , Weibo Wang
- Applicant: FOCHON BIOSCIENCES, LTD.
- Applicant Address: CN Chongqing
- Assignee: FOCHON BIOSCIENCES, LTD.
- Current Assignee: FOCHON BIOSCIENCES, LTD.
- Current Assignee Address: CN Chongqing
- Agency: Ice Miller LLP
- International Application: PCT/CN2019/077976 WO 20190313
- International Announcement: WO2019/174598 WO 20190919
- Main IPC: A61K31/403
- IPC: A61K31/403 ; C07D209/02 ; C07D487/04 ; C07D519/00 ; A61K45/06
![Substituted 2-azabicyclo[3.1.0]hexanes as TRK kinases inhibitors](/abs-image/US/2022/10/04/US11459332B2/abs.jpg.150x150.jpg)
Abstract:
Provided are certain TRK inhibitors of formula (I): pharmaceutical compositions thereof, and methods of use thereof.
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