Invention Grant
- Patent Title: Substances for targeting various selected organs or tissues
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Application No.: US16461313Application Date: 2017-11-15
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Publication No.: US11459358B2Publication Date: 2022-10-04
- Inventor: Peter Christian De Visser , Adriana Marie Aartsma-Rus , Silvana Maria Gerarda Jirka , Peter Abraham Christiaan 'T Hoen , Maria Begoña Aguilera Diez
- Applicant: BioMarin Technologies B.V. , Academisch Ziekenhuis Leiden
- Applicant Address: NL Leiden; NL Leiden
- Assignee: BioMarin Technologies B.V.,Academisch Ziekenhuis Leiden
- Current Assignee: BioMarin Technologies B.V.,Academisch Ziekenhuis Leiden
- Current Assignee Address: NL Leiden; NL Leiden
- Agency: Husch Blackwell LLP
- Priority: EP16199033 20161116
- International Application: PCT/EP2017/079349 WO 20171115
- International Announcement: WO2018/091544 WO 20180524
- Main IPC: C07K7/64
- IPC: C07K7/64 ; A61K47/64 ; A61K47/54 ; A61P9/00 ; A61K49/00 ; C12N15/113

Abstract:
The invention provides conjugates, comprising an organ or tissue targeting moiety linked to a biologically active moiety or linked to a diagnostic moiety. Such a biologically active or diagnostic moiety can be, for example, an oligonucleotide, small interfering RNA, a gene, a virus, a protein, a drug, a small organic molecule, a pharmaceutical, or a detectable agent.
Public/Granted literature
- US20210347825A1 Substances for targeting various selected organs or tissues Public/Granted day:2021-11-11
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