Invention Grant
- Patent Title: Transformant having Entner-Doudoroff pathway and production method for organic compound using same
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Application No.: US17051832Application Date: 2019-03-27
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Publication No.: US11459574B2Publication Date: 2022-10-04
- Inventor: Masayuki Inui , Masako Suda , Naoto Kato , Satoshi Hasegawa , Takahisa Kogure , Toru Jojima
- Applicant: RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH
- Applicant Address: JP Kyoto
- Assignee: RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH
- Current Assignee: RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH
- Current Assignee Address: JP Kyoto
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JPJP2018-088425 20180501
- International Application: PCT/JP2019/013368 WO 20190327
- International Announcement: WO2019/211958 WO 20191107
- Main IPC: C12N15/77
- IPC: C12N15/77 ; C12P7/40

Abstract:
Provided is a method for improving productivity in producing an organic compound in a bacterium that originally does not have an inherent ED pathway. In one aspect, provided is a transformant of a coryneform bacterium that is obtained by introducing the Entner-Doudoroff pathway into the coryneform bacterium as a host. In another aspect, provided is a transformant of a coryneform bacterium that is obtained by introducing, into a coryneform bacterium as a host a gene in which an enzyme having glucose-6-phosphate dehydrogenase activity is encoded, a gene in which an enzyme having 6-phosphogluconate dehydratase activity is encoded, and a gene in which an enzyme having 2-keto-3-deoxy-6-phosphogluconate aldolase activity is encoded.
Public/Granted literature
- US20210054386A1 TRANSFORMANT AND PRODUCTION METHOD FOR ORGANIC COMPOUND USING SAME Public/Granted day:2021-02-25
Information query
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