Modified Fc gamma receptor type III (FcgammaIII, HNA-1) polypeptides and the uses thereof
Abstract:
The invention is directed to engineered Fc gamma receptor type III (FcγII, HNA-1) polypeptides and use of these polypeptides to detect antibodies specific for human neutrophil antigens (HNA). The invention is also directed to methods for the diagnosing and determining susceptibility for developing Transfusion Reaction Acute Lung (TRALI).
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