A system and method which provides RFID enabling for cryo-vials and other cryogenic items is disclosed. The system and method is a two part method wherein first each vial is individually RFID tagged and then a plurality of tagged vials are secured into a cane. The second part comprises creating an RFID tag and attaching the tag to the top of the cane of vials. The individual RFID tags on the vials are then associated with the RFID tag on the cane.