A method and system for image processing is provided. The method for image processing may include: obtaining an image data set, wherein the image data set includes a first set of volume data; and determining, by the at least one processor, a target anatomy of interest based on the first set of volume data. The determining of the target anatomy of interest may include: determining an initial anatomy of interest in the first set of volume data; and editing the initial anatomy of interest to obtain the target anatomy of interest. The target anatomy of interest may include at least one region of interest (ROI) or at least one volume of interest (VOI). The initial anatomy of interest may include at least one ROI or at least one VOI.