Systems, devices, and methods described herein provide one or more radical chemicals generators (RCGs) and/or mini-chambers (M-Cs) that can be used to provide enhanced radical ignition (ERI) in an internal combustion engine. RCGs as described herein can include quenching systems (QSs) that can be configured to quench a flame of combustion products to produce a jet of partial combustion products containing radical species (RS). The jet of partial combustion products can be injected to a main combustion chamber (MCC) of an engine to induce ERI. ERI can proceed under leaner fuel conditions and lower temperatures compared to those needed for conventional thermally induced, fuel oxidation chain initiation reaction processes.