A method and a device for determining an uplink multiplexed time-frequency resource, a storage medium, and a user equipment. The method may include: acquiring indication information of the uplink multiplexed time-frequency resource from a base station, wherein the indication information comprises resource indication information of a frequency domain resource in the uplink multiplexed time-frequency resource; determining resource information of the frequency domain resource based on the resource indication information; and determining resource information of a time domain resource in the uplink multiplexed time-frequency resource at least based on a time domain position of the last symbol of the indication information. Resource information of a time domain resource may be determined based on less information, which facilitates saving signaling overheads of indication information of uplink multiplexed time-frequency resources.