Invention Grant
- Patent Title: AAV vectors targeted to the central nervous system
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Application No.: US16741324Application Date: 2020-01-13
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Publication No.: US11491242B2Publication Date: 2022-11-08
- Inventor: Steven Gray , Thomas McCown
- Applicant: The University of North Carolina at Chapel Hill
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Myers Bigel, P.A.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N7/00 ; A61K9/00 ; A61K35/76 ; C12N15/86 ; C07K14/005 ; A61K31/711 ; C12N15/62
Abstract:
The invention relates to chimeric AAV capsids targeted to the central nervous system, virus vectors comprising the same, and methods of using the vectors to target the central nervous system. The invention further relates to chimeric AAV capsids targeted to oligodendrocytes, virus vectors comprising the same, and methods of using the vectors to target oligodendrocytes.
Public/Granted literature
- US20200206363A1 AAV Vectors Targeted to the Central Nervous System Public/Granted day:2020-07-02
Information query
