Invention Grant
- Patent Title: Mutant alpha-1-antitrypsin compositions and use thereof
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Application No.: US16499534Application Date: 2018-04-02
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Publication No.: US11492390B2Publication Date: 2022-11-08
- Inventor: Eli Chaim Lewis , Yotam Lior
- Applicant: B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY
- Applicant Address: IL Beer-Sheva
- Assignee: B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY
- Current Assignee: B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY
- Current Assignee Address: IL Beer-Sheva
- Agency: The Roy Gross Law Firm, LLC
- Agent Roy Gross
- International Application: PCT/IL2018/050385 WO 20180402
- International Announcement: WO2018/185756 WO 20181011
- Main IPC: C07K14/81
- IPC: C07K14/81 ; A61P17/02 ; A61P29/00 ; A61K38/00

Abstract:
The present invention provides mutant alpha 1-antitrypsin proteins, pharmaceutical compositions comprising the same, and methods of use thereof in treatment of subjects with an inflammatory disease or disorder.
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