Invention Grant
- Patent Title: TREM2 stabilizing antibodies
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Application No.: US16601070Application Date: 2019-10-14
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Publication No.: US11492402B2Publication Date: 2022-11-08
- Inventor: Verena Brand , Dominik Feuerbach , Fabrizio Gasparini , Nathalie George , Eveline Schaadt , Derya Shimshek , Honnappa Srinivas , Markus Waldhuber , Rainer Wilcken
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agency: K&L Gates LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61P25/28 ; A61K39/395 ; A61K39/00 ; C12N7/00 ; C12N15/70

Abstract:
The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.
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