Invention Grant
- Patent Title: Bispecific checkpoint inhibitor antibodies
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Application No.: US16435375Application Date: 2019-06-07
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Publication No.: US11492407B2Publication Date: 2022-11-08
- Inventor: Matthew Bernett , Gregory Moore , John Desjarlais , Michael Hedvat , Christine Bonzon , Alex Nisthal , Umesh S. Muchhal
- Applicant: Xencor, Inc.
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Morgan, Lewis & Bockius, LLP
- Agent Louis-Vu T. Nguyen; Christopher J. Betti
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K14/735 ; C12N15/861 ; A61K39/00 ; A61P35/00
Abstract:
The present invention is directed to heterodimeric anti-LAG-3×anti-CTLA-4. Also provided are nucleic acid compositions that encode the antibodies, expression vector compositions that include the nucleic acids, and host cells that include the expression vector compositions.
Public/Granted literature
- US20190389954A1 BISPECIFIC CHECKPOINT INHIBITOR ANTIBODIES Public/Granted day:2019-12-26
Information query
