- Patent Title: Automatic dishwashing detergent composition comprising a protease
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Application No.: US17066686Application Date: 2020-10-09
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Publication No.: US11492571B2Publication Date: 2022-11-08
- Inventor: Philip Frank Souter , Eva Maria Perez-Prat Vinuesa , Michelle Jackson , Carly Pickering , Viktor Yuryevich Alekseyev , Lilia Maria Babe , Frits Goedegebuur , Thijs Kaper , Sina Pricelius , Sander Van Stigt Thans , Harm Mulder , Nils Henning Redestig , Lydia Dankmeyer , Michael Stoner , Adam Garske , Roopa Santosh Ghirnikar
- Applicant: The Procter & Gamble Company
- Applicant Address: US OH Cincinnati
- Assignee: The Procter & Gamble Company
- Current Assignee: The Procter & Gamble Company
- Current Assignee Address: US OH Cincinnati
- Agent Carolyn S. Powell; George H. Leal
- Main IPC: C11D3/386
- IPC: C11D3/386 ; C11D3/395 ; C12N9/54

Abstract:
A phosphate-free automatic dishwashing cleaning composition comprising a protease wherein the protease has at least 80%, preferably at least 85%, more preferably at least 90% and especially at least 96% identity with the amino acid sequence of SEQ ID NO:1 or with the amino acid sequence of SEQ ID NO:2 and wherein the protease comprises amino acid substitutions selected from the group consisting of: (i) at least two amino acid substitutions selected from the group consisting of: X198G/A/K/L/Q/R/T/V/S/L, X207Q, X211Q/N and X212Q in combination with at least three amino acid substitutions selected from the group consisting of: X039E, X074D, X099R, X126A, X127E and X128G; or (ii) X039E-X074D-X099R-X116R-X126A-X127E-X128G-X211Q; X039E-X074D-X099R-X126A-X127E-X128G-X211N; X039E-X074D-X099R-X126A-X127E-X128G-X211Q; X039E-X074D-X099R-X126A-X127E-X128G-X207Q; or (iii) any of the proteases of (i) and (ii) further comprising at least one amino acid substitution selected from X242D and X256E; or (iv) X039E-X074D-X099R-X126A-X127E-X128G-X256E; using the SEQ ID NO:2 numbering.
Public/Granted literature
- US20210122997A1 AUTOMATIC DISHWASHING DETERGENT COMPOSITION COMPRISING A PROTEASE Public/Granted day:2021-04-29
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