Invention Grant
- Patent Title: Modified bialaphos resistance acetyltransferase compositions and uses thereof
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Application No.: US16340579Application Date: 2017-10-17
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Publication No.: US11492636B2Publication Date: 2022-11-08
- Inventor: Bastien Christ , Jing-Ke Weng
- Applicant: Whitehead Institute for Biomedical Research
- Applicant Address: US MA Cambridge
- Assignee: Whitehead Institute for Biomedical Research
- Current Assignee: Whitehead Institute for Biomedical Research
- Current Assignee Address: US MA Cambridge
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- International Application: PCT/US2017/056968 WO 20171017
- International Announcement: WO2018/075507 WO 20180426
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C12N9/10
Abstract:
Provided herein are engineered bialaphos resistance acetyltransferase variants having a modified acetyltransferase activity against tryptophan or aminoadipate, or both, as compared to a wildtype bialaphos resistance acetyltransferase (e.g., BAR or PAT). Also provided are transgenic plants comprising a bialaphos resistance acetyltransferase variant as well as methods of making such transgenic plants.
Public/Granted literature
- US20190249188A1 Modified Bialaphos Resistance Acetyltransferase Compositions And Uses Thereof Public/Granted day:2019-08-15
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