Invention Grant
- Patent Title: Infrared-optical hybrid imaging technology for all-digital histopathology
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Application No.: US16733610Application Date: 2020-01-03
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Publication No.: US11493323B2Publication Date: 2022-11-08
- Inventor: Martin Schnell , Paul Scott Carney , Rohit Bhargava
- Applicant: The Board of Trustees of the University of Illinois , Asociación Centro De Investigación Cooperativa en Nanociencias, CIC Nanogune
- Applicant Address: US IL Urbana; ES Donostia-San Sebastián
- Assignee: The Board of Trustees of the University of Illinois,Asociación Centro De Investigación Cooperativa en Nanociencias, CIC Nanogune
- Current Assignee: The Board of Trustees of the University of Illinois,Asociación Centro De Investigación Cooperativa en Nanociencias, CIC Nanogune
- Current Assignee Address: US IL Urbana; ES Donostia-San Sebastián
- Agency: Sunstein LLP
- Main IPC: G01N21/47
- IPC: G01N21/47 ; G01B9/02091 ; G01B9/02004 ; A61B5/00 ; G01B9/02015

Abstract:
Methods and apparatus are provided for imaging a response of a sample to radiative heating. A method in accordance with one embodiment has steps of: illuminating a first area of the sample with a radiative heating beam; illuminating a portion of the first area with a probe beam; collecting light exiting the sample due to interaction of the probe beam with the sample; superimposing the light exiting the sample with a reference beam derived from the probe beam, wherein the reference is characterized by an optical phase relative to the probe beam; detecting a spatial portion of the light exiting the sample and the reference beam with at least one detector to generate an interference signal; and processing the interference signal to obtain an image of the sample associated with absorption of the radiative heating beam.
Public/Granted literature
- US20200217643A1 Infrared-Optical Hybrid Imaging Technology for All-Digital Histopathology Public/Granted day:2020-07-09
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