Invention Grant
- Patent Title: Activation of bioluminescene by structural complementation
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Application No.: US16851841Application Date: 2020-04-17
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Publication No.: US11493504B2Publication Date: 2022-11-08
- Inventor: Andrew S. Dixon , Lance Encell , Mary Hall , Keith Wood , Monika Wood , Marie Schwinn , Brock F. Binkowski , Hicham Zegzouti , Nidhi Nath , Subhanjan Mondal , Said Goueli , Poncho Meisenheimer , Thomas Kirkland , James Unch , Dileep K. Pulukkunat , Matthew Robers , Melanie Dart , Thomas Machleidt
- Applicant: Promega Corporation
- Applicant Address: US WI Madison
- Assignee: Promega Corporation
- Current Assignee: Promega Corporation
- Current Assignee Address: US WI Madison
- Agency: Casimir Jones SC
- Agent David W. Staple
- Main IPC: G01N31/00
- IPC: G01N31/00 ; G01N33/53 ; G01N33/533 ; C07K14/435 ; C12Q1/66 ; C07K7/08 ; C12N9/02 ; G01N33/542 ; G01N33/58 ; A61K51/08
Abstract:
Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.
Public/Granted literature
- US20200292534A1 ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION Public/Granted day:2020-09-17
Information query
