A method for a hypervisor to implement flow-based local egress in a multisite datacenter is disclosed. The method comprises: determining whether a first data packet of a first data flow has been received. If the first data packet has been received, then the hypervisor determines a MAC address of a first local gateway in a first site of a multisite datacenter that communicated the first data packet, and stores the MAC address of the first local gateway and a 5-tuple for the first data flow. Upon determining that a response for the first data flow has been received, the hypervisor determines whether the response includes the MAC address of the first local gateway. If the response includes a MAC address of another local gateway, then the hypervisor replaces, in the response, the MAC address of another local gateway with the MAC address of the first local gateway.