The present disclosure provides a method of transmitting and receiving a signal by a user equipment (UE) in a wireless communication system. The method may include: transmitting an uplink (UL) signal including a reference signal (RS) to a base station; measuring a self-interference (SI) signal based on the UL signal; and transmitting a message based on the measured SI signal. The message may include a request for RS change or information about the state of the measured SI signal.