An active noise reduction system and method, and a storage medium are provided. In the system, a first signal acquisition circuitry acquires an external noise signal at a noise cancellation spot, and transmits the acquired external noise signal to a noise control system including a first frequency nonlinear transformation circuitry, a first filter circuitry and an inverter. The first frequency nonlinear transformation circuitry receives the external noise signal, and expands at least one target frequency band of the external noise signal based on a frequency nonlinear transformation mapping function to generate a first transformed external noise signal, the first filter circuitry filters the first transformed external noise signal to generate a filtered external noise signal, and the inverter performs inversion on the filtered external noise signal to generate a noise cancellation signal; and the signal output circuitry receives and outputs the noise cancellation signal to cancel an actual noise.