Methods and systems for performing in-loop luma mapping with chroma scaling are described. One of the methods includes receiving a chrome block and a luma block associated with a picture. The method also includes determining luma scaling information associated with the luma block. The method also includes determining a luma scaling factor of the luma block based on the luma scaling information. The method also includes determining the chroma scaling factor based on a value of the luma scaling factor. The method also includes processing residuals of the chroma block using the chroma scaling factor.