- Patent Title: Baroreflex vascular sympathetic nervous activity detection device, baroreflex vascular sympathetic nervous activity detection program, and baroreflex vascular sympathetic nervous activity detection method
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Application No.: US16498839Application Date: 2018-03-30
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Publication No.: US11517207B2Publication Date: 2022-12-06
- Inventor: Yuichi Kato
- Applicant: SAPPORO MEDICAL UNIVERSITY
- Applicant Address: JP Sapporo
- Assignee: SAPPORO MEDICAL UNIVERSITY
- Current Assignee: SAPPORO MEDICAL UNIVERSITY
- Current Assignee Address: JP Sapporo
- Agency: Muncy, Geissler, Olds & Lowe, P.C.
- Priority: JPJP2017-067476 20170330
- International Application: PCT/JP2018/013525 WO 20180330
- International Announcement: WO2018/181851 WO 20181004
- Main IPC: A61B5/021
- IPC: A61B5/021 ; A61B5/0295 ; A61B5/00

Abstract:
A vascular baroreflex-related sympathetic activity (VBRSA) detection device, a VBRSA detection program, and a VBRSA detection method capable of detecting in a simple and non-invasive manner VBRSA, which is sympathetic nervous activity of a blood vessel involved in a baroreflex function, are provided. The VBRSA detection device detects the VBRSA based on pulse wave data on a biological artery and a beat interval corresponding to the pulse wave data. The VBRSA detection device includes a VBRSA-series detecting unit that detects, as a VBRSA series indicative of VBRSA, a series where, from among the series in which the beat interval increases or decreases by n (n is a natural number 3 or more) beats consecutively, a correlation coefficient for the beat interval and pulse wave data is greater than any positive threshold up to the (n-1)-th beat and the correlation coefficient at the n-th beat falls to or below the threshold.
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