Invention Grant
- Patent Title: Drug therapy to inhibit chemotherapy-induced adverse effects and related pharmaceutical compositions, diagnostics, screening techniques and kits
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Application No.: US15611908Application Date: 2017-06-02
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Publication No.: US11517587B2Publication Date: 2022-12-06
- Inventor: Barbara Ehrlich , Sara Rockwell , Jennifer Benbow
- Applicant: YALE UNIVERSITY
- Applicant Address: US CT New Haven
- Assignee: YALE UNIVERSITY
- Current Assignee: YALE UNIVERSITY
- Current Assignee Address: US CT New Haven
- Agent Henry D. Coleman; R. Neil Sudol
- Main IPC: A61K31/337
- IPC: A61K31/337 ; A61K33/14 ; A61K38/57 ; A61K45/06 ; A61K31/20 ; A61K31/416 ; A61K31/19 ; A61K31/437 ; A61K31/5415 ; A61K33/00 ; G01N33/50
Abstract:
The invention provides a method of treatment comprising reducing therapy-induced adverse effects (TIAE), including chemotherapy-induced adverse effects (CIAE), such as chemotherapy-induced peripheral neuropathy (CIPN) and/or chemotherapy-induced cardiovascular adverse effects (CICAE) in a subject being treated with a CIAE-inducing anti-cancer active ingredient by co-administering to the subject a pharmaceutically effective amount of a NCS-1-protective composition. Related pharmaceutical compositions, diagnostics and screening techniques are also provided.
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