Invention Grant
- Patent Title: Pharmaceutical composition for the parenteral administration of ultrashort-effective β-adrenoreceptor antagonists
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Application No.: US16860336Application Date: 2020-04-28
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Publication No.: US11517624B2Publication Date: 2022-12-06
- Inventor: Rudolf Stefan Widmann
- Applicant: AOP ORPHAN PHARMACEUTICALS AG
- Applicant Address: AT Vienna
- Assignee: AOP ORPHAN PHARMACEUTICALS AG
- Current Assignee: AOP ORPHAN PHARMACEUTICALS AG
- Current Assignee Address: AT Vienna
- Agency: Norton Rose Fulbright US LLP
- Priority: ATA2107/2007 20071221
- Main IPC: A61K47/40
- IPC: A61K47/40 ; A61K9/00 ; A61K31/24 ; A61K31/5377 ; A61K31/724 ; B82Y5/00 ; A61K47/69

Abstract:
The present invention relates to a pharmaceutical composition in the form of a storage-stable solution for the parenteral administration of ultrashort-effective β-adrenoreceptor antagonists, comprising a) an ultrashort-effective β-adrenoreceptor antagonist and/or a pharmaceutically acceptable salt thereof, b) water, and c) a cyclodextrin and/or a functional cyclodextrin derivative. The composition according to the invention has high stability, even without the presence of additional adjuvants.
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