- Patent Title: Nanofiber paste for growth factor delivery and bone regeneration
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Application No.: US15293666Application Date: 2016-10-14
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Publication No.: US11517648B2Publication Date: 2022-12-06
- Inventor: Mark Trosper McClendon , Samuel I. Stupp , Sungsoo Lee , Erin L. Hsu
- Applicant: Northwestern University
- Applicant Address: US IL Evanston
- Assignee: Northwestern University
- Current Assignee: Northwestern University
- Current Assignee Address: US IL Evanston
- Agency: Casimir Jones SC
- Agent David W. Staple
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61L27/54 ; A61L27/48 ; A61L27/52

Abstract:
Provided herein are compositions comprising a composite of peptide amphiphiles and biocompatible particles and methods of use thereof for treatment of bone and/or tissue defects. In particular, compositions comprise a slurry paste of a peptide amphiphile nanofiber solution mixed with solid biocompatible particles, and find use in tissue/bone regeneration, growth factor delivery, and/or cell delivery.
Public/Granted literature
- US20170106120A1 NANOFIBER PASTE FOR GROWTH FACTOR DELIVERY AND BONE REGENERATION Public/Granted day:2017-04-20
Information query
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