A breathable barrier fabric that is heat sealable and minimizes lint generation without impacting the fabric's overall breathability, comfort and barrier protection, and that can be used to manufacture Helmke Category II or better cleanroom garments suitable for use in ISO Class 3 cleanroom environments and other hygienic applications. The breathable barrier fabric has a composite laminate structure including an inner monolithic film layer made from a breathable polymer bonded to first and second outer spunbond layers comprising thermoplastic bicomponent fibers each having an outer glazed surface where the thermoplastic bicomponent fibers are at least partially flattened.