Methods and systems may provide for technology to initiate an injection of ozone for a predetermined cycle time into a cabin of a vehicle via a heating ventilation and air conditioning (HVAC) subsystem of the vehicle only when the vehicle is in a locked state and a window-closed state, the vehicle cabin is vacant, and the vehicle is in park. The technology may also cease the injection of the ozone into the cabin in response to an override request detected before expiration of the predetermined cycle time and maintains the vehicle in the locked state for a predetermined wait time after the injection of the ozone into the cabin is ceased.