Invention Grant
- Patent Title: Benzamide compound and preparation method, use, and pharmaceutical composition thereof
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Application No.: US16966433Application Date: 2019-01-30
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Publication No.: US11518744B2Publication Date: 2022-12-06
- Inventor: Heng Xu , Xiaoguang Chen , Songwen Lin , Ming Ji , Nina Xue , Deyu Wu , Jing Jin
- Applicant: INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES
- Applicant Address: CN Beijing
- Assignee: INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES
- Current Assignee: INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES
- Current Assignee Address: CN Beijing
- Agency: Merchant & Gould P.C.
- Priority: CN201810090951.0 20180130
- International Application: PCT/CN2019/073942 WO 20190130
- International Announcement: WO2019/149223 WO 20190808
- Main IPC: C07D213/53
- IPC: C07D213/53 ; C07D401/12 ; C07D405/12 ; C07D409/12
Abstract:
The present invention relates to a benzamide compound and a preparation method, use and pharmaceutical composition thereof. The benzamide compound represented by formula (I) is a STAT3 inhibitor, and can be used to prevent and/or treat a disease related to STAT3 activity, such as a tumor, autoimmune disease, renal disease, cardiovascular disease, inflammation, metabolic/endocrine dysfunction, and neurological disease.
Public/Granted literature
- US20210047270A1 BENZAMIDE COMPOUND AND PREPARATION METHOD, USE, AND PHARMACEUTICAL COMPOSITION THEREOF Public/Granted day:2021-02-18
Information query
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