Invention Grant
![Anti-Wolbachia pyrido[2,3-d]pyrimidine compounds](/docs/US/2022-12-06/US11518760B2/abs.jpg.600x600.jpg)
- Patent Title: Anti-Wolbachia pyrido[2,3-d]pyrimidine compounds
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Application No.: US16478281Application Date: 2018-01-17
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Publication No.: US11518760B2Publication Date: 2022-12-06
- Inventor: Stephen A. Ward , Mark J. Taylor , Paul M. O'Neill , Weiqian David Hong , Farid Benayoud
- Applicant: Liverpool School of Tropical Medicine , The University of Liverpool , Eisai R&D Management Co., Ltd.
- Applicant Address: GB Liverpool; GB Liverpool; JP Bunkyo-Ku
- Assignee: Liverpool School of Tropical Medicine,The University of Liverpool,Eisai R&D Management Co., Ltd.
- Current Assignee: Liverpool School of Tropical Medicine,The University of Liverpool,Eisai R&D Management Co., Ltd.
- Current Assignee Address: GB Liverpool; GB Liverpool; JP Bunkyo-Ku
- Agency: Foley Hoag LLP
- Agent David P. Halstead; Benjamin A. Vaughan
- Priority: GB1700814 20170117
- International Application: PCT/IB2018/000216 WO 20180117
- International Announcement: WO2018/134685 WO 20180726
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D239/86 ; C07D495/04
![Anti-Wolbachia pyrido[2,3-d]pyrimidine compounds](/abs-image/US/2022/12/06/US11518760B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to compounds of Formulae (I) and (II) as defined herein, and salts and solvates thereof. The present invention also relates to pharmaceutical compositions comprising compounds of Formulae (I) and (II), and to the use of compounds of Formulae (I) and (II) in the treatment or prevention of filarial worm infection, as well as other diseases or conditions in which filarial worm infection is implicated.
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