Invention Grant
- Patent Title: Sesquiterpenoid analogs
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Application No.: US16531185Application Date: 2019-08-05
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Publication No.: US11518770B2Publication Date: 2022-12-06
- Inventor: Mingji Dai , Dexter Cameron Davis , Alexander Adibekian , Dominic Gregor Hoch , Zhong-Yin Zhang
- Applicant: Purdue Research Foundation
- Applicant Address: US IN West Lafayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West Lafayette
- Agency: Purdue Research Foundation
- Main IPC: C07D493/10
- IPC: C07D493/10
Abstract:
The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging drugs for cancers.
Public/Granted literature
- US20200040000A1 NOVEL SESQUITERPENOID ANALOGS Public/Granted day:2020-02-06
Information query
