Invention Grant
- Patent Title: Anti-ROR1 antibodies and methods of making and using thereof
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Application No.: US16615116Application Date: 2018-06-22
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Publication No.: US11518815B2Publication Date: 2022-12-06
- Inventor: Ole Olsen , Phil Tan , Dong Xia , David Jellyman , Brian Kovacevich , Bill Brady , Blair Renshaw , Zeren Gao , Yi Zhu
- Applicant: SYSTIMMUNE, INC. , SICHUAN BAILI PHARMACEUTICAL CO. LTD.
- Applicant Address: US WA Redmond; CN Chengdu
- Assignee: SYSTIMMUNE, INC.,SICHUAN BAILI PHARMACEUTICAL CO. LTD.
- Current Assignee: SYSTIMMUNE, INC.,SICHUAN BAILI PHARMACEUTICAL CO. LTD.
- Current Assignee Address: US WA Redmond; CN Chengdu
- Agent Zhihua Han
- International Application: PCT/US2018/039152 WO 20180622
- International Announcement: WO2019/005636 WO 20190103
- Main IPC: A61K45/06
- IPC: A61K45/06 ; C07K16/28 ; A61K39/395 ; A61K39/00
Abstract:
The application provides anti-ROR1 monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.
Public/Granted literature
- US20210277109A1 ANTI-ROR1 ANTIBODIES AND METHODS OF MAKING AND USING THEREOF Public/Granted day:2021-09-09
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