Invention Grant
- Patent Title: Methods and compositions for treating cancer using peptide nucleic acid-based agents
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Application No.: US16988395Application Date: 2020-08-07
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Publication No.: US11518996B2Publication Date: 2022-12-06
- Inventor: Jeffrey H. Rothman , Gary K. Schwartz
- Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
- Applicant Address: US NY New York
- Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
- Current Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
- Current Assignee Address: US NY New York
- Agency: Bryan Cave Leighton Paisner LLP
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61P35/00 ; C07K14/00 ; C12Q1/6886 ; A61K38/00 ; G01N33/574
Abstract:
The present invention provides compositions and methods for treating cancer with peptide nucleic acid agents. In some embodiments, the present invention provides methods and compositions relating to peptide nucleic acid agents that target oncogenes. For example, the present invention provides compositions, including pharmaceutical compositions, comprising agents specific for BRAF V600E inhibition, or fragments or characteristic portions thereof. The present invention further provides various therapeutic and/or diagnostic methods of using BRAF V600E specific peptide nucleic acid agents and/or compositions.
Public/Granted literature
- US20200370049A1 METHODS AND COMPOSITIONS FOR TREATING CANCER USING PEPTIDE NUCLEIC ACID-BASED AGENTS Public/Granted day:2020-11-26
Information query
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