Invention Grant
- Patent Title: System, method, computer-accessible medium, and apparatus facilitating ultra-high resolution optical coherence tomography for automated detection of diseases
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Application No.: US17162720Application Date: 2021-01-29
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Publication No.: US11519713B2Publication Date: 2022-12-06
- Inventor: Christine Hendon , Richard Ha , Diana Mojahed , Hanina Hibshoosh , James McLean
- Applicant: The Trustees of Columbia University in the City of New York
- Applicant Address: US NY New York
- Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee Address: US NY New York
- Agency: Hunton Andrews Kurth LLP
- Main IPC: G01B11/02
- IPC: G01B11/02 ; G01B9/02091 ; H01L33/00 ; A61B3/10

Abstract:
An exemplary system for generating an image(s) of a sample(s) can include, for example, an imaging arrangement that can include a superluminescent diode (SLD) configured to generate a radiation(s) to be provided to the sample(s), and a spectrometer configured to (i) sample an A-line sampling rate of at least about 200 kHz, (ii) receive a resultant radiation from the sample(s) based on the sampling rate, and (iii) generate information based on the resultant radiation, and a computer hardware arrangement configured to generate the image(s) of the sample(s) based on the information received from the spectrometer. The imaging arrangement can be an interferometric imaging arrangement, which can be an optical coherence tomography imaging (OCT) arrangement. The computer hardware arrangement can be further configured to facilitate a plurality of b-scan acquisitions of the sample(s) and facilitate the b-scan acquisitions in order to generate the image(s).
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