Control system and method for managing transport of vehicles in a warehouse. A network of cameras provide coverage over the route way network by capturing images and sending image data to a central control unit which processes the images and generates signals to control the movement of robot slaves. The control system also includes a calibration mechanism to calibrate a map of the network of routes and an obstruction matrix function. The robot slaves include a safety override mechanism to control the robot slaves autonomously and independently in case of detecting an obstacle or an unexpected hazard in a path of its movement along a route of the warehouse network.