Aspects of the disclosure relate to controlling an autonomous vehicle to respond to a detected collision. An autonomous vehicle control system may receive sensor data associated with an autonomous vehicle in which the autonomous vehicle control system is installed. The autonomous vehicle control system may analyze the sensor data in real-time as the sensor data is received and may detect an occurrence of a collision involving the autonomous vehicle. In response to detecting the occurrence of the collision, the autonomous vehicle control system may generate claim information based on the sensor data and may process the claim information based on at least one insurance profile maintained by the autonomous vehicle control system. Then, the autonomous vehicle control system may generate a claim notification based on processing the claim information and may send the claim notification to a vehicle management computer system.