Embodiments of the present disclosure relate to heart sound measurements using mobile devices. In an embodiment, a medical system for monitoring heart sounds of a subject comprises a medical device configured to obtain, during a first sampling interval, a first physiological signal. The medical system further comprises a mobile device comprising an accelerator, wherein the accelerator is configured to obtain, during a second sampling interval, a second physiological signal. And, the medical system comprises an analysis component configured to extract heart sounds data from the second physiological signal.