Invention Grant
- Patent Title: Method for producing capsules comprising at least one water-soluble or hydrophilic substance, and resulting capsules
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Application No.: US16495438Application Date: 2018-03-21
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Publication No.: US11540979B2Publication Date: 2023-01-03
- Inventor: Damien Demoulin , Ludivine Mousnier , Jamie Walters
- Applicant: CAPSUM
- Applicant Address: FR Marseilles
- Assignee: CAPSUM
- Current Assignee: CAPSUM
- Current Assignee Address: FR Marseilles
- Agency: Pearne & Gordon LLP
- Priority: FR1752326 20170321
- International Application: PCT/EP2018/057218 WO 20180321
- International Announcement: WO2018/172434 WO 20180927
- Main IPC: A61K8/02
- IPC: A61K8/02 ; B01J13/18

Abstract:
The present invention relates to a method for preparing solid microcapsules that comprises of the following steps: a) the preparation of a composition C1, comprising at least one water-soluble or hydrophilic substance dispersed in a hydrophobic phase; b) the addition, under stirring, of the said composition C1 in a polymeric composition C2, the compositions C1 and C2 being immiscible with each other, whereby an emulsion (E1) is obtained; c) the addition, under stirring, of the emulsion (E1) in a composition C3, the compositions C2 and C3 being immiscible with each other, whereby a double emulsion (E2) is obtained; d) the application of a shear to the emulsion (E2), whereby a double emulsion (E3) is obtained; and e) the polymerisation of the composition C2, whereby solid microcapsules dispersed in the composition C3 are obtained.
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