Invention Grant
- Patent Title: Compounds and compositions for the treatment of neurodegenerative and inflammatory diseases
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Application No.: US16968890Application Date: 2019-02-13
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Publication No.: US11541023B2Publication Date: 2023-01-03
- Inventor: Chahrazade El Amri , Feryel Soualmia , Nicolas Masurier , Sabrina Aït Amiri , Brahim Nait Oumesmar , Cyrille Deboux
- Applicant: SORBONNE UNIVERSITE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE , ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS , INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE , UNIVERSITE DE MONTPELLIER , ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER
- Applicant Address: FR Paris; FR Paris; FR Paris; FR Paris; FR Paris; FR Montpellier; FR Montpellier
- Assignee: SORBONNE UNIVERSITE,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE,ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS,INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE,UNIVERSITE DE MONTPELLIER,ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER
- Current Assignee: SORBONNE UNIVERSITE,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE,ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS,INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE,UNIVERSITE DE MONTPELLIER,ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER
- Current Assignee Address: FR Paris; FR Paris; FR Paris; FR Paris; FR Paris; FR Montpellier; FR Montpellier
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: FR1851206 20180213
- International Application: PCT/FR2019/050321 WO 20190213
- International Announcement: WO2019/158859 WO 20190822
- Main IPC: A61K31/167
- IPC: A61K31/167 ; A61P25/28
Abstract:
The invention relates to compounds exhibiting kallikrein inhibitory activity, and to compositions comprising at least one of these compounds for use in the treatment of diseases or disorders in which kallikrein activity is dysregulated, particularly neurodegenerative and inflammatory diseases.
Public/Granted literature
- US20210046026A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE AND INFLAMMATORY DISEASES Public/Granted day:2021-02-18
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