Invention Grant
- Patent Title: Methods of attenuating an immune response by inhibition of BFL1
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Application No.: US15733346Application Date: 2019-01-14
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Publication No.: US11541073B2Publication Date: 2023-01-03
- Inventor: David A. Hildeman , Andrew Herr , Suhas G. Kallapur , Jarek Meller , Alexander Thorman
- Applicant: Children's Hospital Medical Center
- Applicant Address: US OH Cincinnati
- Assignee: Children's Hospital Medical Center
- Current Assignee: Children's Hospital Medical Center
- Current Assignee Address: US OH Cincinnati
- Agency: KDB Firm PLLC
- International Application: PCT/US2019/013470 WO 20190114
- International Announcement: WO2019/140372 WO 20190718
- Main IPC: A61K31/35
- IPC: A61K31/35 ; A61K31/713 ; A61K31/7105 ; C07K16/18 ; C12N15/113 ; A61K31/655 ; A61K9/127 ; B82Y5/00
Abstract:
The disclosure provides methods of modulating an immune response by inhibiting BFL1, and related methods for treating and preventing diseases and disorders characterized by inflammation, especially neutrophil induced inflammation.
Public/Granted literature
- US20210113604A1 METHODS OF TREATMENT BY INHIBITION OF BFL1 Public/Granted day:2021-04-22
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