Invention Grant
- Patent Title: Compositions and methods for treating Alzheimer's disease
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Application No.: US16820269Application Date: 2020-03-16
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Publication No.: US11541086B2Publication Date: 2023-01-03
- Inventor: William L. Klein , Diana Jerusalinsky , Sergio T. Ferreira , Maria Clara Selles , Adriano S. Sebollela
- Applicant: Northwestern University , Consejo Nacional de Investigaciones Científicas y Técnicas , Universidade Federal do Rio de Janeiro
- Applicant Address: US IL Evanston; AR Buenos Aires; BR Rio de Janeiro
- Assignee: Northwestern University,Consejo Nacional de Investigaciones Científicas y Técnicas,Universidade Federal do Rio de Janeiro
- Current Assignee: Northwestern University,Consejo Nacional de Investigaciones Científicas y Técnicas,Universidade Federal do Rio de Janeiro
- Current Assignee Address: US IL Evanston; AR Buenos Aires; BR Rio de Janeiro
- Agency: Casimir Jones SC
- Agent David W. Staple
- Main IPC: A61K35/76
- IPC: A61K35/76 ; C07K16/18 ; A61K9/00
Abstract:
Provided herein are antibodies against amyloid-beta (Aβ) oligomers, and methods of use thereof for the treatment of Alzheimer's disease (AD). In particular, neuronal expression of single-chain variable fragment (scFv) antibodies against Aβ oligomers is provided as a therapeutic approach in the treatment of AD.
Public/Granted literature
- US20200289589A1 COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE Public/Granted day:2020-09-17
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