Disclosed herein are formulations, methods, and kits of formulations for inhibiting, ameliorating, delaying the onset of, reducing the likelihood of, treating, and/or preventing metabolic syndrome, and/or increasing energy levels. The formulations have at least one extract from a tart cherry, at least one antioxidant vitamin, at least one polyphenolic compound, and at least one prebiotic. Also disclosed are methods of making the formulations.