Invention Grant
- Patent Title: Glucose sensitive insulins and uses thereof
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Application No.: US17274802Application Date: 2019-09-18
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Publication No.: US11541122B2Publication Date: 2023-01-03
- Inventor: Thomas Hoeg-Jensen , Alice Ravn Madsen , Thomas Kruse , Per Sauerberg , Anthony Murray , Andrew Michael Chapman , Anthony Peter Davis
- Applicant: Ziylo Limited
- Applicant Address: GB Gatwick
- Assignee: Ziylo Limited
- Current Assignee: Ziylo Limited
- Current Assignee Address: GB Gatwick
- Agent Jianjie Hu
- Priority: EP18195490 20180919,EP19176911 20190528
- International Application: PCT/EP2019/074987 WO 20190918
- International Announcement: WO2020/058322 WO 20200326
- Main IPC: A61K47/55
- IPC: A61K47/55 ; C07K14/62 ; A61P5/50
Abstract:
The present invention provides glucose sensitive insulin derivatives comprising a macrocycle, a glucose mimetic and human insulin or an analogue thereof, and their pharmaceutical use. Furthermore, the invention relates to pharmaceutical compositions comprising such glucose sensitive insulin derivatives, and to the use of such compounds for the treatment or prevention of medical conditions relating to diabetes.
Information query
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