Invention Grant
- Patent Title: BCKDK inhibitors
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Application No.: US16912828Application Date: 2020-06-26
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Publication No.: US11542270B2Publication Date: 2023-01-03
- Inventor: Samit Kumar Bhattacharya , Leanne Marie Buzon , Kevin James Filipski , David Andrew Griffith , Bethany Lyn Kormos , Luis Angel Martinez-Alsina , Russell Alan Miller , Matthew Richard Reese , Rachel Jane Roth Flach , Yuan Zhang
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Main IPC: C07D495/04
- IPC: C07D495/04 ; A61K31/155 ; A61K31/4985 ; A61K31/7048 ; A61K45/06

Abstract:
Described herein are compounds of Formula I, wherein R1, R2, and R3 are defined herein, their use as branched-chain alpha keto acid dehydrogenase kinase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, diabetes, NASH and heart failure.
Public/Granted literature
- US20210024536A1 BCKDK INHIBITORS Public/Granted day:2021-01-28
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