Invention Grant
- Patent Title: Solid forms of ceftolozane and processes for preparing
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Application No.: US16304955Application Date: 2017-06-01
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Publication No.: US11542279B2Publication Date: 2023-01-03
- Inventor: Kevin Matthew Maloney , Eric M. Sirota , Richard J. Varsolona , Donald R. Gauthier, Jr. , Hong Ren
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Patricia A. Shatynski; John C. Todaro
- International Application: PCT/US2017/035345 WO 20170601
- International Announcement: WO2017/213944 WO 20171214
- Main IPC: C07D501/56
- IPC: C07D501/56 ; A61K9/19 ; A61K31/431 ; A61K31/546
Abstract:
The instant invention is related to a novel solid form of ceftolozane sulfate (the DMAc solvate of ceftolozane sulfate (Form 3)), compositions comprising ceftolozane sulfate DMAc solvate (Form 3), synthesis of Form 3 and an improved crystallization process using Form 3 to prepare ceftolozane sulfate Form 2. Novel compositions also include ceftolozane sulfate solid Form 3 and/or other crystalline and amorphous solid forms of ceftolozane.
Public/Granted literature
- US20220056045A1 SOLID FORMS OF CEFTOLOZANE AND PROCESSES FOR PREPARING Public/Granted day:2022-02-24
Information query
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