Alkyldiphenylmethane protective agent
Abstract:
Provided is an alkyldiphenylmethane protective agent, which can prevent solidification or insolubilization of a compound by protecting a functional group of the compound to achieve easy separation and purification after a reaction.
An alkyldiphenylmethane compound represented by general formula (1): wherein Y represents —OR19 (wherein R19 represents a hydrogen atom or an active ester-type protecting group), —NHR20 (wherein R20 represents a hydrogen atom, a C1-6 linear or branched alkyl group, or an aralkyl group), isocyanate group, an azide group, or a halogen atom, Z represents a C1-4 linear or branched alkyl group, an alkenyl group, or a cycloalkyl group, at least one of R1 to R10 represents a group represented by formula (2): —O—R11—X-A  (2) and the others each independently represent a hydrogen atom, a halogen atom, a C1-4 alkyl group, or a C1-4 alkoxy group; R11 represents a C1-16 linear or branched alkylene group; X represents O or CONR21 (wherein R21 represents a hydrogen atom or a C1-4 alkyl group); and A represents, for example, a group represented by formula (3): wherein R12, R13, and R14 may be the same or different and each independently represent a C1-6 linear or branched alkyl group or an optionally substituted aryl group; R15 represents a single bond or a C1-3 linear or branched alkylene group; and R16, R17, and R18 each independently represent a C1-3 linear or branched alkylene group.
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