Invention Grant
- Patent Title: Methods of treating cancer using antibodies and molecules that bind to BTN1A1 or BTN1A1-ligands
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Application No.: US16618764Application Date: 2018-06-05
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Publication No.: US11542331B2Publication Date: 2023-01-03
- Inventor: Stephen Sunghan Yoo , Ezra Myung Chul Chung , Yong-Sik Bong , Yong-Soo Kim
- Applicant: STCUBE & CO., INC.
- Applicant Address: KR Seoul
- Assignee: STCUBE & CO., INC.
- Current Assignee: STCUBE & CO., INC.
- Current Assignee Address: KR Seoul
- Agency: Jones Day
- International Application: PCT/US2018/036026 WO 20180605
- International Announcement: WO2018/226671 WO 20181213
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K16/28

Abstract:
Provided herein are methods for treating cancer using molecules having an antigen binding fragment that immunospecifically binds to BTN1A1 or a BTN1A1 ligand, such as anti-BTN1A1 antibodies or anti-BTN1A1 ligand antibodies. Also provided herein are BTN1A1 ligands, such as Galectin-1, Galectin-9, Neuropilin-2, and B- and T-Lymphocyte Attenuator.
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